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A New Twist

What sets the final size and shape of chiral filament bundles (many stranded, self-twisting, yarn-like structures) implicated in such diseases as Alzheimer’s, Parkinson’s, and Sickle Cell Anemia? Researchers at UMass Amherst use computers at the MGHPCC to unravel rules of twisted bundle morphology.

In a recent issue of Nature Materials, polymer scientists Greg Grason, Douglas Hall and Isaac Bruss at the University of Massachusetts Amherst, with Justin Barone at Virginia Tech, identify for the first time the factors that govern the final morphology of self-assembling chiral filament bundles.

Prof Greg Grayson
UMass Amherst, Department of Polymer Science and Engineering

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