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Microplastic-Free by Design

Image credit: MIT
Chemical engineers use MGHPCC computers to develop biodegradable materials to replace environmentally harmful microplastics.

Linzixuan (Rhoda) Zhang and colleagues from the Jaklenec Lab developed a biodegradable alternative to microplastics commonly used in health and beauty products. These new microparticles, made from poly(β-amino ester) polymers, are designed to dissolve in the stomach, making them safe for ingestion and ideal for applications like vitamin and nutrient delivery in food fortification. The research addresses both environmental concerns—by replacing persistent microplastics—and global health challenges, such as micronutrient deficiencies.

To support this work, the team utilized high-performance computing resources at the MIT SuperCloud and Lincoln Laboratory Supercomputing Center, both part of the MGHPCC consortium. These computational tools enabled the modeling and simulation of particle behavior under various conditions, accelerating the design and testing process. The project showcases how shared supercomputing infrastructure can drive innovation in sustainable materials science and public health.

 

Linzixuan (Rhoda) Zhang conducted this research as part of her PhD in Chemical Engineering at the Massachusetts Institute of Technology and is now an R&D Project Manager at Sinclair Pharma.

Research projects

A Future of Unmanned Aerial Vehicles
Yale Budget Lab
Volcanic Eruptions Impact on Stratospheric Chemistry & Ozone
Towards a Whole Brain Cellular Atlas
Tornado Path Detection
The Kempner Institute - Unlocking Intelligence
The Institute for Experiential AI
Taming the Energy Appetite of AI Models
Surface Behavior
Studying Highly Efficient Biological Solar Energy Systems
Software for Unreliable Quantum Computers
Simulating Large Biomolecular Assemblies
SEQer - Sequence Evaluation in Realtime
Revolutionizing Materials Design with Computational Modeling
Remote Sensing of Earth Systems
Quantum Computing in Renewable Energy Development
Pulling Back the Quantum Curtain on ‘Weyl Fermions’
New Insights on Binary Black Holes
NeuraChip
Network Attached FPGAs in the OCT
Monte Carlo eXtreme (MCX) - a Physically-Accurate Photon Simulator
Modeling Hydrogels and Elastomers
Modeling Breast Cancer Spread
Impact of Marine Heatwaves on Coral Diversity
IceCube: Hunting Neutrinos
Genome Forecasting
Global Consequences of Warming-Induced Arctic River Changes
Exact Gravitational Lensing by Rotating Black Holes
Evolution of Viral Infectious Disease
Evaluating Health Benefits of Stricter US Air Quality Standards
Ephemeral Stream Water Contributions to US Drainage Networks
Energy Transport and Ultrafast Spectroscopy Lab
Electron Heating in Kinetic-Alfvén-Wave Turbulence
Discovering Evolution’s Master Switches
Dexterous Robotic Hands
Developing Advanced Materials for a Sustainable Energy Future
Detecting Protein Concentrations in Assays
Denser Environments Cultivate Larger Galaxies
Deciphering Alzheimer's Disease
Dancing Frog Genomes
Cyber-Physical Communication Network Security
Asteroid Data Mining
Analyzing the Gut Microbiome
Adaptive Deep Learning Systems Towards Edge Intelligence
Accelerating Rendering Power
ACAS X: A Family of Next-Generation Collision Avoidance Systems
Computation + Machine Intelligence | Wu Tsai Institute
Computational Modeling of Biological Systems
Computational Molecular Ecology
Social Capital and Economic Mobility
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