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Bone Ratios and Big Data

Using a combination of classic paleontology methods, machine-learning algorithms, and 3D modeling techniques Caleb Gordon studies the evolution of aquatic and macrocarnivorous lifestyles in ancient reptiles.

A recent paper details a machine-learning framework Gordon and co-authors developed to predict aquatic habits and soft-tissue limb features—like flippers—in extinct amniotes using fossilized bone proportions. By analyzing over 11,000 linear measurements and geometric morphometric data from 747 specimens, the team found that relative hand length is a powerful predictor of flipper presence and aquatic lifestyle, achieving over 90% accuracy across mammals and reptiles.

Their phylogenetic models revealed that while interdigital webbing cannot be reliably inferred from bones alone, flippered limbs and highly aquatic habits correlate strongly with specific forelimb proportions. Applying these models to extinct species clarified long-standing debates about the ecology of marine reptiles, showing multiple independent origins of flippers and aquatic lifestyles in groups like mosasaurs, ichthyosaurs, and thalattosaurs.

This work required extraordinary computational resources. Gordon ran multi-day job arrays involving 10,000 CPUs in parallel, consuming hundreds of thousands of CPU-hours on Yale’s Grace HPC cluster, housed at the Massachusetts Green High Performance Computing Center (MGHPCC). These resources enabled complex phylogenetic regressions and simulations across millions of tree configurations -demonstrating how research computing is transforming paleobiology by revealing hidden evolutionary patterns in Earth’s history.

Caleb M. Gordon
Now a Postdoctoral Researcher at the Florida Museum of Natural History, Gordon received his PhD in the Department of Earth and Planetary Sciences at Yale University in 2025

Research projects

A Future of Unmanned Aerial Vehicles
Yale Budget Lab
Volcanic Eruptions Impact on Stratospheric Chemistry & Ozone
Towards a Whole Brain Cellular Atlas
Tornado Path Detection
The Kempner Institute - Unlocking Intelligence
The Institute for Experiential AI
Taming the Energy Appetite of AI Models
Surface Behavior
Studying Highly Efficient Biological Solar Energy Systems
Software for Unreliable Quantum Computers
Simulating Large Biomolecular Assemblies
SEQer - Sequence Evaluation in Realtime
Revolutionizing Materials Design with Computational Modeling
Remote Sensing of Earth Systems
Quantum Computing in Renewable Energy Development
Pulling Back the Quantum Curtain on ‘Weyl Fermions’
New Insights on Binary Black Holes
NeuraChip
Network Attached FPGAs in the OCT
Monte Carlo eXtreme (MCX) - a Physically-Accurate Photon Simulator
Modeling Hydrogels and Elastomers
Modeling Breast Cancer Spread
Impact of Marine Heatwaves on Coral Diversity
IceCube: Hunting Neutrinos
Genome Forecasting
Global Consequences of Warming-Induced Arctic River Changes
Exact Gravitational Lensing by Rotating Black Holes
Evolution of Viral Infectious Disease
Evaluating Health Benefits of Stricter US Air Quality Standards
Ephemeral Stream Water Contributions to US Drainage Networks
Energy Transport and Ultrafast Spectroscopy Lab
Electron Heating in Kinetic-Alfvén-Wave Turbulence
Discovering Evolution’s Master Switches
Dexterous Robotic Hands
Developing Advanced Materials for a Sustainable Energy Future
Detecting Protein Concentrations in Assays
Denser Environments Cultivate Larger Galaxies
Deciphering Alzheimer's Disease
Dancing Frog Genomes
Cyber-Physical Communication Network Security
Asteroid Data Mining
Analyzing the Gut Microbiome
Adaptive Deep Learning Systems Towards Edge Intelligence
Accelerating Rendering Power
ACAS X: A Family of Next-Generation Collision Avoidance Systems
Neurocognition at the Wu Tsai Institute, Yale
Computational Modeling of Biological Systems
Computational Molecular Ecology
Social Capital and Economic Mobility
Building for Floods
Better Pathogen Targeting
Tracking Environmental Health Risks
AI for Cancer Diagnosis
Microplastic-Free by Design
Supporting Data-intensive Social Science
Sailing the Symbiosis Seascape
Wrangle Range Modeling
Shining a Light on Dark Matter
Grid Responsive Data Centers
Multifunctional 3D-Printed Materials
AI Pareidolia
Computing Hidden Health Threats from Heat
Staving off the Banana Apocalypse
CRISPR Mice, Smarter Science
Naval and Ocean Renewable Energy Hydrodynamics
AI That Speaks Human About Health
A Safer Way to See Inside Cells
How Monkeys - and Machines - See in 3D
FlowER: AI for Predicting Chemical Reactions
Bone Ratios and Big Data
Supercomputers Reveal Ancient Atmospheric Battle
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